Cherubism treated with intranasal calcitonin: A case report and literature review

Cherubism treated with intranasal calcitonin: A case report and literature review

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Cherubism is a rare benign disease, clinically characterized by progressive, asymptomatic, and bilateral expansion of the jaws.Both familial and sporadic cases have been reported.Typically, first signs and 4 Way Hotplate Control Switch symptoms appear in early childhood between 2 and 5 years of age, followed by gradual progression of lesions until puberty and remission before the 4th-5th decades.A treatment protocol for cherubism has not been yet standardized and treatment options vary between conventional surgical and non-invasive approaches.

The purpose of this clinical report is to present a comprehensive diagnostic and conservative treatment approach of a 7-years old male with familial cherubism.At age 7 with asymptomatic mild bilateral swelling of the cheeks were observed.The Bike Parts - Derailleurs - Front team approach management of the case was based on intranasal calcitonin for 2 years combined with surgical removal of impacted teeth, orthodontics, and prosthodontics.Complete regression was achieved, which was persistent for 8 years post treatment.